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Enantioselective pharmacodynamics of the nonsteroidal antiinflammatory drug ketoprofen: In vitro inhibition of human platelet cyclooxygenase activity

โœ Scribed by Peter J. Hayball; Roger L. Nation; Felix Bochner


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
475 KB
Volume
4
Category
Article
ISSN
0899-0042

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Neutrophils contain a collagenase that is stored in a latent form within the specific granule. With cellular activation, the latent enzyme is activated in association with the production of a variety of oxidants, including hypochlorous acid. We evaluated 4 nonsteroidal antiinflammatory drugs (NSAIDs