✦ LIBER ✦

Enantioselective oxidation of thioethers: synthesis of trans-2-N,N-dialkylacetamide-1,3-dithiolanes-S-oxide and their use in asymmetric aldol-type reactions

✍ Scribed by Martina Corich; Fulvio Di Furia; Giulia Licini; Giorgio Modena

Publisher: Elsevier Science
Year: 1992
Tongue: French
Weight: 139 KB
Volume: 33
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)79595-5

No coin nor oath required. For personal study only.

✦ Synopsis

trans-Z-NN-dialkylacetamide-1,3-dith 2 have been obtained in high d.e. (>9!kl) and e.e. (up to 94%. >98% after crystallization) by enantioselective oxidation [Ti(i-PrOId. (+)-DET, r-BuOOH]. The aldol-type addition of the magnesium enolate of the N,Ndiethyl derivative (-)-2b to Lso-butyraldehyde affonied good chemical yields of a single diastereomer.

📜 SIMILAR VOLUMES

Preparation of Novel N-Sulfonylated (S,S

Preparation of Novel N-Sulfonylated (S,S)-2,3-Diaminosuccinate-Type Chiral Auxiliaries and Application to an Asymmetric 1,3-Dipolar Cycloaddition Reaction of Nitrile Oxides to Allyl Alcohol.

✍ Masakazu Serizawa; Yutaka Ukaji; Katsuhiko Inomata 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 22 KB 👁 1 views

ChemInform Abstract: Synthesis of N-Prop

ChemInform Abstract: Synthesis of N-Propionylated (S)-(-)-2-(Pyrrolidin-2-yl)propan-2-ol and Its Use as a Chiral Auxiliary and Selectivity Marker in Asymmetric Aldol Reactions.

✍ Erik Hedenstroem; Frederik Andersson; Mats Hjalmarsson 📂 Article 📅 2000 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views