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Enantioselective one-pot three-component synthesis of propargylamines catalyzed by copper(I)–pyridine bis-(oxazoline) complexes

✍ Scribed by Alakesh Bisai; Vinod K. Singh

Book ID
113928785
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
558 KB
Volume
68
Category
Article
ISSN
0040-4020

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Practical Highly Enantioselective Synthe
Practical Highly Enantioselective Synthesis of Propargylamines through a Copper-Catalyzed One-Pot Three-Component Condensation Reaction
✍ Nina Gommermann; Paul Knochel 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 277 KB 👁 2 views

## Abstract The one‐pot three‐component reaction of terminal alkynes, aldehydes and secondary amines in the presence of copper(I) bromide/quinap is reported. The reaction scope has been determined and a broad variety of all three components has been used, which afforded the corresponding propargyla