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Enantioselective Mukaiyama-Michael Reaction of Silyl Enol Ethers to 2-Enoylpyridine N -Oxides Catalyzed by Copper- Bis(oxazoline) Complex

✍ Scribed by George, Jimil; Reddy, Basi V. Subba


Book ID
120419088
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
261 KB
Category
Article
ISSN
1615-4150

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Enantioselective mukaiyama-michael react
✍ Anna Bernardi; Giorgio Colombo; Carlo Scolastico πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 French βš– 236 KB

The conjugate addition of propionate silylketcne acetal 1 to 2-carbomethoxy cyclopentenone is promoted by bis(oxazoline)-Cu(ll) complexes with high diastcreosclectivity and good enantiomeric excesses. The absolute configuration of the product can bc controlled by varying the copper counterion. A ca