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Enantioselective Michael reactions. Stereoselective addition of enolates of phenmenthol esters to crotonates

✍ Scribed by E.J. Corey; Richard T. Peterson


Book ID
104233285
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
248 KB
Volume
26
Category
Article
ISSN
0040-4039

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A highly stereoselective Michael reactio
✍ Masahiko Yamaguchi; Michinori Tsukamoto; Shinya Tanaka; Ichiro Hirao πŸ“‚ Article πŸ“… 1984 πŸ› Elsevier Science 🌐 French βš– 244 KB

Under a proper reaction condition, simple ester enolates add to d,e-unsaturated esters highly stereoselectively to give erythro or threoglutarates. Previously, we have shown that lithium enolates derived from simple monoesters react with fi,p-unsaturated esters to give glutarates in high yiela. 1)