Enantioselective Lewis Acid Catalyzed Mukaiyama—Michael Reactions of Acyclic Enones. Catalysis by allo-Threonine-Derived Oxazaborolidinones.
✍ Scribed by Xiaowei Wang; Shinya Adachi; Hiroyoshi Iwai; Hiroshi Takatsuki; Katsuhiro Fujita; Mikako Kubo; Akira Oku; Toshiro Harada
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 196 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
In the presence of 2,6-diisopropylphenol and t-BuOMe (1 equiv. each), asymmetric Mukaiyama-Michael reaction of a variety of benzalacetone derivatives 2 with silyl ketene acetal 3 is efficiently catalyzed by O-(2-naphthoyl)-N-tosyl-(L)-allo-threonine-derived B-phenyloxazaborolidinone 1 (10 mol%) to g
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