✦ LIBER ✦

Enantioselective hydrolysis of α-amino acid esters in the presence of polymer catalysts containing (S)-hydroxyproline groupings and copper(II) or nickel(II) ions

✍ Scribed by I.A. Yamskov; B.B. Berezin; L.A. Belchich; V.A. Davankov

Publisher: Elsevier Science
Year: 1979
Tongue: English
Weight: 166 KB
Volume: 15
Category: Article
ISSN: 0014-3057
DOI: 10.1016/0014-3057(79)90037-5

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✦ Synopsis

Asymmetric polymers containing metal-chelating (S)-hydroxyproline groups in cross-linked polystyrene (I) and acrylamide (ll) matrices were used as catalysts for hydrolysis of or-amino acid esters. The hydrolysis catalysed by polymers I and II, complexed with Cu and Ni ions, displayed in many cases significant enantioselectivity. The values of activation parameters for hydrolysis of LeuOMe in the presence of polymer II in Ni form were calculated.