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Enantioselective Hydrogenation Using Heterogeneous Modified Catalysts: An Update

✍ Scribed by Martin Studer; Hans-Ulrich Blaser; Christian Exner


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
591 KB
Volume
345
Category
Article
ISSN
1615-4150

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πŸ“œ SIMILAR VOLUMES


Enantioselective synthesis of ethyl nipe
✍ H.-U Blaser; H HΓΆnig; M Studer; C Wedemeyer-Exl πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 81 KB

Ethyl nicotinate was hydrogenated to ethyl nipecotinate in two steps. In the first step, the starting material was converted to the 1,4,5,6-tetrahydro derivative with PdrC and hydrogen in 76% yield. The hydrogenation of this intermediate was investigated with both unmodified and 10,11-dihydrocinchon