Enantioselective formal synthesis of antitumor agent (+)-ottelione A
β Scribed by Mi Young Lee; Kyung Hwa Kim; Shuai Jiang; Yoo Hyun Jung; Jae Yi Sim; Geum-Sook Hwang; Do Hyun Ryu
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- French
- Weight
- 111 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The enantioselective formal synthesis of a natural antitumor product, (+)-ottelione A, was achieved through a catalytic enantioselective Diels-Alder strategy. These endeavors have led to the synthesis of a variety of synthetic analogues of this biologically potent natural product.
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