Enantioselective extraction of mandelic acid enantiomers byL-dipentyl tartrate andβ-cyclodextrin as binary chiral selectors

✍ Scribed by F. P. Jiao; X. Q. Chen; W. G. Hu; F. R. Ning; K. L. Huang

• Book ID: 111491066
• Publisher: Versita
• Year: 2007
• Tongue: English
• Weight: 218 KB
• Volume: 61
• Category: Article
• ISSN: 0366-6352
• DOI: 10.2478/s11696-007-0041-4

✦ Synopsis

Abstract

A new binary chiral selector system effective for the enantioselective extraction of racemic mandelic acid is presented. While L-dipentyl tartrate and β-cyclodextrin had a very low enantioselectivity as single selectors, a preferential extraction of D-mandelic acid to the organic phase was found in the binary selector system. Using decanol as organic solvent and pH of a phoshate buffer equal to 2.3, the distribution coefficients of D-and L-mandelic acids as high as 14.9 and 7.0, respectively, and the enantioselectivity value of 2.1 were found at optimum concentration of β-cyclodextrin.