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Enantioselective, Copper(I)-Catalyzed Three-Component Reaction for the Preparation of Propargylamines.

✍ Scribed by Nina Gommermann; Christopher Koradin; Kurt Polborn; Paul Knochel


Publisher
John Wiley and Sons
Year
2004
Weight
212 KB
Volume
35
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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## Abstract The one‐pot three‐component reaction of terminal alkynes, aldehydes and secondary amines in the presence of copper(I) bromide/quinap is reported. The reaction scope has been determined and a broad variety of all three components has been used, which afforded the corresponding propargyla