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Enantioselective conjugate additions of organolithiums to BHA enoates mediated by A chiral ligand

โœ Scribed by Yasutomi Asano; Akira Iida; Kiyoshi Tomioka


Book ID
108386360
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
220 KB
Volume
38
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


Enantioselective addition of organolithi
โœ Pher G. Andersson; Fredrik Johansson; David Tanner ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 888 KB

The C2-symmetric bis(aziridine) ligands 1 -5 have been screened in the enantioselective addition of organolithium reagents to imines. Ligand 1 (used in stoichiometric amounts) was found to be superior in terms of chemical yield and enantioselectivity, the best result being 90\*70 yield and 89% e.e.