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Enantioselective Conjugate Addition of Dialkylzinc Reagents to Cyclic and Acyclic Enones Catalyzed by Chiral Copper Complexes of New Phosphorus Amidites

✍ Scribed by André H. M. de Vries; Auke Meetsma; Prof. Dr. Ben L. Feringa


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
370 KB
Volume
35
Category
Article
ISSN
0044-8249

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Synthesis of New Chiral Aryl Diphosphite
✍ Lailai Wang; Yue-Ming Li; Chiu-wing Yip; Liqin Qiu; Zhongyuan Zhou; Albert S. C. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 146 KB 👁 1 views

## Abstract New chiral aryl diphosphite ligands based on the pyranoside backbones of glucose and galactose were prepared. These ligands were tested in the Cu‐catalyzed asymmetric conjugate addition of diethylzinc to cyclic enones with up to 88% ee. The stereoselectivity was found to be dependent on