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Enantioselective approach to the steroid skeleton by conjugate addition of alkenylcopper-phosphine complexes. Total syntheses of estrone methyl ether and its 7-alkylated derivative

✍ Scribed by Takayuki Doi; Katsuya Shimizu; Takashi Takahashi; Jiro Tsuji; Keiji Yamamoto


Book ID
104222285
Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
267 KB
Volume
31
Category
Article
ISSN
0040-4039

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✦ Synopsis


Enantioselective syntheses of estrone methyl ether and its 7-alkylated derivative by the conjugate addition of alkenylcopper-phosphine complexes and discussions for the diastereoselectivity in the intramolecular Diels-Alder reaction of the o-quinodimethane derivative on the basis of MM2 transition structure models are presented.