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Enantioselective Alkynylation of Ketones Promoted by β-Sulfonamide Alcohol-Titanium Complexes

✍ Scribed by Ming Ni; Yi-Feng Zhou; Chao Chen; Jiang-Ke Xu; Rui Wang


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
54 KB
Volume
25
Category
Article
ISSN
0256-7660

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The enantioselective formation of C À C bonds is an area of intense research. [1,2] The asymmetric addition of alkynyl reagents to aldehydes is very useful for the synthesis of chiral secondary propargyl alcohols, which are important building blocks for many chiral organic compounds. [3] Several stu