Enantiopure D-, L- (and 2-epi-) Purpurosamine C-Type Glycosyl Donors from Racemic Acrolein Dimer − Biocatalytic Resolution

✍ Scribed by Silke Erbeck; Xifu Liang; Richard Krieger; Horst Prinzbach

• Book ID: 102657822
• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 802 KB
• Volume: 1998
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/(sici)1099-0690(199803)1998:3<481::aid-ejoc481>3.0.co;2-z

✦ Synopsis

Both enantiomers of purpurosamine C-type glycosyl donors nitration"). In two cases (rac-23β: methyl 6-O-acetyl-2,3,4-trideoxy-2α-trifluoroacetylamino-β-D/L-hexopyranoside, rac-32: [(ent)-9, (ent)-10, (ent)-11] and of a 2-azido epimer [(ent)-14] with a modified pattern of protecting groups have been methyl 6-O-acetyl-2β-azido-2,3,4-trideoxy-β-D/L-hexopyranoside), efficient resolution has been achieved biocata-prepared from racemic 3,4-dihydro-2H-pyran-2-carbaldehyde (acrolein dimer, rac-1, "indirect