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Enantiopure 2-(Trifluoromethyl)-1,2,3,4-tetrahydronaphthalene-1,2-diols from a Tartaric Acid Derived Scaffold

✍ Scribed by Fabien Massicot; Jean Nonnenmacher; Fabienne Grellepois; Charles Portella


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
314 KB
Volume
2010
Category
Article
ISSN
1434-193X

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A Concise Synthesis of 2-Amino-1,2,3,4-t
✍ Süleyman Göksu; Cavit Kazaz; Yaşar Sütbeyaz; Hasan Seçen 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 69 KB

## Abstract 2‐Amino‐1,2,3,4‐tetrahydronaphthalene‐6,7‐diol (**2**; 6,7‐ADTN) was synthesized starting from naphthalene‐2,3‐diol in seven steps and with an overall yield of 44%. Methylation of naphthalene‐2,3‐diol with dimethyl sulfate, followed by __Friedel____Crafts__ acylation with AcCl, gave 2‐