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Enantiomerically Enrichred Cyclopropene Derivatives: Versatile Building Blocks in Asymmetric Synthesis

✍ Scribed by Ilan Marek; Samah Simaan; Ahmad Masarwa


Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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Alkylation of 1,4-cyclohexanedione monoethylene acetal SAMP-hydrazone with various electrophiles (10 examples given) and subsequent cleavage of the hydrazones with saturated oxalic acid furnished highly enantiomerically enriched alpha-alkylated mono-protected 1,4-cyclohexanedione derivatives in high