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Enantiomeric separation of acidic compounds of pharmaceutical interest by capillary electrochromatography employing glycopeptide antibiotic stationary phases

โœ Scribed by Salvatore Fanali; Paolo Catarcini; Carla Presutti


Book ID
108339317
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
143 KB
Volume
994
Category
Article
ISSN
1873-3778

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## Use of vancomycin silica stationary phase in packed capillary electrochromatography: III. Enantiomeric separation of basic compounds with the polar organic mobile phase The separation of basic compounds into their enantiomers was achieved using capillary electrochromatography in 50 or 75 mm inn

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Capillary electrophoresis has been used for the enantiomeric resolution of several basic compounds of pharmaceutical interest employing a background electrolyte containing pepsin as chiral selector. The separations have been performed in a polyacrylamide-coated capillary to suppress or minimize the