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Enantiomeric resolution with a new chiral stationary phase of 7-chloro-3-methyl-3,4-dihydro-2H1,2,4-benzothiadiazine S,S-dioxide, a cognition-enhancing benzothiadiazine derivative

✍ Scribed by Doncho P. Uzunov; Ilia Zivkovich; William H. Pirkle; Erminio Costa; Alessandro Guidotti

Book ID: 102916670
Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 855 KB
Volume: 84
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600840807

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## Abstract A novel chiral stationary phase (CSP) for HPLC was prepared by bonding (__R__)‐1‐phenyl‐2‐(4‐methylphenyl)ethylamine amide derivative of (__S__)‐valine to aminopropyl silica gel through a 2‐amino‐3,5‐dinitro‐1‐carboxamido‐benzene unit. The CSP was used for the separation of some amino a