Enantiomeric Resolution of Benzoxazolinonic Aminoalcohols, Potential Adrenergic Ligands, by LC and CE

Enantioseparation of benzoxazolinone ami

Enantioseparation of benzoxazolinone aminoalcohols and their aminoketone precursors, potential adrenergic ligands, by analytical and preparative liquid chromatography on amylose chiral stationary phases and characterization of the enantiomers

✍ Emmanuelle Lipka; Claude Vaccher; Jean-Paul Bonte 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB

## Abstract To obtain milligram amounts of the enantiomers of benzoxazolinone derivatives to be tested for binding to adrenergic sites, analytical HPLC methods using derivatized amylose chiral stationary phases were developed for the direct enantioseparation of benzoxazolinone aminoalcohols and the