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Enantiomer separation of hydrophobic amino compounds by high-performance liquid chromatography using crown ether dynamically coated chiral stationary phase

✍ Scribed by Yoshio Machida; Hiroyuki Nishi; Kouji Nakamura


Book ID
108341642
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
204 KB
Volume
830
Category
Article
ISSN
1873-3778

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High performance liquid chromatographic
✍ Uwe Conrad; Bezhan Chankvetadze; Gerhard K. E. Scriba πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 526 KB

## Abstract A chiral stationary phase (CSP) based on (–)‐(18‐crown‐6)‐2,3,11,12‐tetracarboxylic acid was evaluated for the direct resolution of the enantiomers of dipeptides and tripeptides. The type and concentration of the acid and the methanol content were optimized with regard to retention time