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Enantiomer Effects of Huperzine A on the Aryl Acylamidase Activity of Human Cholinesterases

✍ Scribed by Sultan Darvesh; Ryan Walsh; Earl Martin

Book ID
110422571
Publisher
Springer
Year
2003
Tongue
English
Weight
80 KB
Volume
23
Category
Article
ISSN
0272-4340

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## Abstract L‐Huperzine‐A (Hup‐A), a natural cholinesterase inhibitor (ChEI) derived from the Chinese herb Huperzia serrata, was administered systemically (i.p.) or locally through the microdialysis probe into the rat cortex. Systemic Hup‐A significantly increased acetylcholine (ACh) levels above b