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Empirical calculations of peptide-water interactions. Structural aspects of hydration

✍ Scribed by Genest, Monique; Vovelle, Françoise; Ptak, Marius

Book ID
123442108
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
300 KB
Volume
63
Category
Article
ISSN
0300-9084

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In aqueous solution, melittin structure, investigated by CD and 'H-nmr, depends on pH and ionic composition, which also regulate the aggregation state of the peptide. When interacting with phospholipids, however, melittin exhibits a right-handed helical conformation without any evidence of oligomeri