Empiric antibiotic use—aztreonam as a model
✍ Scribed by Stuart Levin
- Book ID
- 115682925
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 423 KB
- Volume
- 88
- Category
- Article
- ISSN
- 1555-7162
No coin nor oath required. For personal study only.
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One hundred and seventy-one consecutive febrile episodes occurring in 130 neutropenic adult patients with hematological malignancies (mainly acute leukemia) were empirically treated with a combination antibiotic therapy consisting of ceftazidime (100 mg/kg/day) + amikacin (1 5 mg/kg/day). Of these,
In a prospective, randomized trial, 205 febrile episodes in granulocytopenic cancer patients were treated with ceftazidime with or without tobramycin (C +/- T), both agents being administered only if the initial granulocyte count was below 200/microliters, or ceftazidime plus piperacillin (C + P). T