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Emodin accelerates osteoblast differentiation through phosphatidylinositol 3-kinase activation and bone morphogenetic protein-2 gene expression

✍ Scribed by Su-Ui Lee; Hye Kyoung Shin; Yong Ki Min; Seong Hwan Kim


Book ID
116576324
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
750 KB
Volume
8
Category
Article
ISSN
1567-5769

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## Abstract Syringetin (3,5,7,4′‐tetrahydroxy‐3β€²,5β€²dimethoxyflavone), a flavonoid derivative, is present in grape and wine. By means of alkaline phosphatase (ALP) activity, osteocalcin, and type I collagen ELISA, we have shown that syringetin exhibits a significant induction of differentiation in M