[Cancer Drug Discovery and Development]
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Melillo, Giovanni
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Article
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2013
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Springer New York
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English
β 668 KB
βββThe imbalance between rapidly proliferating tumor cells and inadequate and inefficient tumor vasculature leads to a decrease in oxygen levels (hypoxia and/or anoxia) in tumor tissues. Intra-tumor hypoxia profoundly affects the biological behavior of cancer cells, which become resistant to convent