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Emerging complexities of APOBEC3G action on immunity and viral fitness during HIV infection and treatment

✍ Scribed by Mahdis Monajemi, Claire F Woodworth, Jessica Benkaroun, Michael Grant, Mani Larijani


Book ID
119907983
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
563 KB
Volume
9
Category
Article
ISSN
1742-4690

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## Abstract Allogeneic immunity is one of the most potent natural immune responses. APOBEC3G (A3G) is an intracellular anti‐viral factor that deaminates cytidine to uridine. Allogeneic stimulation of human CD4^+^ T cells __in vitro__ upregulated A3G mRNA and a significant correlation was found betw