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Emergency treatment of variceal haemorrhage

✍ Scribed by S. Sagar; I. D. Harrison; R. Brearley; R. Shields

Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
294 KB
Volume
66
Category
Article
ISSN
0007-1323

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✦ Synopsis

Abstract

For the initial control of haemorrhage from oesophageal varices, two methods of vasopressin administration have been comparedβ€”the conventional bolus of 20 units and a low dose infusion of 0Β·4 units per minute.

Twenty patients bleeding from oesophageal varices, confirmed by endoscopy, were allocated into either treatment group (10 in each). Vasopressin infusion stopped bleeding in 86 per cent of the episodes in contrast to 12Β·5 per cent (P < 0Β·01) with bolus doses. Balloon tamponade with a Sengstaken-Blakemore tube was used to control bleeding in only 2 episodes in patients on infusion and in 10 episodes in patients on bolus doses of vasopressin (P < 0Β·05). Our study confirms that low dose vasopressin infusion is more effective in controlling bleeding from oesophageal varices than conventional bolus doses.

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