Although occult hepatitis B virus (HBV) infection in individuals without detectable hepatitis B surface antigen (HBsAg) may occur and has been reported to be common in patients with chronic hepatitis C, the related molecular mechanisms remain unknown. With the polymerase chain reaction, serum HBV DN
✦ LIBER ✦
Emergence of hepatitis B virus mutants in the PreS/S and PreC/C genes during follow up of an HBeAg positive chronic HBV infection
✍ Scribed by Tran, A.; Kremsdorf, D.; Petit, H.A.; Housset, C.; Bréchot, C.
- Book ID
- 122038086
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 140 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0168-8278
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## Abstract A direct binding enzyme‐linked immunosorbent assay (ELISA) was established for quantitative determination of serum IgM antibodies towards a synthetic peptide corresponding to a selected segment (14‐21) of the preS2‐gene product containing an immunodominant linear B‐cell epitope. The pre