✦ LIBER ✦

Embryotoxicity studies of tri-n-butyltin(IV) complexes of 5-[(E)-2-(aryl)-1-diazenyl]-2-hydroxybenzoic acid and 2-[(E)-2-(3-formyl-4-hydroxyphenyl)-1-diazenyl] benzoic acid on sea urchin development

✍ Scribed by Tushar S. Basu Baul; Wandondor Rynjah; Keisham Surjit Singh; Claudia Pellerito; Paolo D'Agati; Lorenzo Pellerito

Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 242 KB
Volume: 19
Category: Article
ISSN: 0268-2605
DOI: 10.1002/aoc.971

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✦ Synopsis

Abstract

The toxicity studies of free 5‐[(E)‐2‐(aryl)‐1‐diazenyl]‐2‐hydroxybenzoic acid and 2‐[(E)‐2‐(3‐formyl‐4‐hydroxyphenyl)‐1‐diazenyl]benzoic acid and their tri‐n‐butyltin(IV) complexes were evaluated by using sea urchin early developmental stages as recommended model organisms for toxicity tests. The novel complexes, as the parent tri‐n‐butyltin(IV) chloride (TBTCl), caused mitosis block and induced high embryonic mortality in sea urchin. Copyright © 2005 John Wiley & Sons, Ltd.

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