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Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN

โœ Scribed by Ji Young Heo; Hyun Jung Kim; Sung-Moo Kim; Kyung-Ran Park; Sang-Yoon Park; Seong Won Kim; Dongwoo Nam; Hyeung-Jin Jang; Seok-Geun Lee; Kyoo Seok Ahn; Sung-Hoon Kim; Bum Sang Shim; Seung-Hoon Choi; Kwang Seok Ahn


Book ID
116335661
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
793 KB
Volume
308
Category
Article
ISSN
0304-3835

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## Abstract The activation of signal transducers and activators of transcription 3 (STAT3) has been closely linked with the proliferation, survival, invasion, and angiogenesis of hepatocellular carcinoma (HCC) and represents an attractive target for therapy. In the present report, we investigated w