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Elusive platelet ADP receptor identified

✍ Scribed by Kathryn Senior


Book ID
117291152
Publisher
The Lancet
Year
2001
Tongue
English
Weight
55 KB
Volume
357
Category
Article
ISSN
0140-6736

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Extracellular nucleotides have been implicated in a number of physiologic functions. Nucleotides act on cell surface receptors known as P2 receptors of which several subtypes have been cloned. Both ATP and ADP are stored in platelets and are released upon platelet activation. During vascular injury,