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Elucidation of the function and role of cAMP sensor Epac2A in insulin secretion

✍ Scribed by Tadao Shibasaki

Book ID: 118303293
Publisher: Springer Japan
Year: 2012
Tongue: English
Weight: 517 KB
Volume: 3
Category: Article
ISSN: 2190-1678
DOI: 10.1007/s13340-012-0094-7

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## Abstract Ion channels in beta cells regulate electrical and secretory activity in response to metabolic, pharmacologic, or neural signals by controlling the permeability to K^+^ and Ca^2+^. The ATP‐sensitive K^+^ channels act as a switch that responds to fuel secretagogues or sulfonylureas to in