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eLS || Genetics of the Autosomal Dominant Spinocerebellar Ataxias

✍ Scribed by Corral-Juan, Marc


Book ID
121214247
Publisher
John Wiley & Sons, Ltd
Year
2011
Tongue
English
Weight
267 KB
Category
Article
ISBN-13
9780470015902

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✦ Synopsis


Articles In The Fields Of Biochemistry And Physiology, Cell Biology, Developmental Biology, Ecology, Evolution, Genetics, Immunology, Molecular Biology, Neuroscience, Microbiology And Virology, Plant Science, Structural Biology, Science And Society. Includes Index.


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Distinct distribution of autosomal domin
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## Abstract Dominant ataxias show wide geographic variation. We analyzed 108 dominant families and 123 sporadic ataxia patients from Mexico for mutations causing SCA1–3, 6–8, 10, 12, 17 and DRPLA. Only 18.5% of dominant families remained undiagnosed; SCA2 accounted for half (45.4%), followed by SCA