Elimination reaction of 2-bromo-3-acetoxy-3-aryl-1-phenylpropanones
✍ Scribed by J.M. Agoff; M.C. Cabaleiro
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- French
- Weight
- 152 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
53 51 49 48 54 \*Compounds Id, e were separated chromatographically on a silica-gel column using hexane eluent. \*\*Yield based on compounds IIa-c.
5~ -Vinyl phenyl sulfone reacts with aldehydes to yield sulfonylated secondary allylic alcohols which are converted to either primary allylic bromides, or secondary allylic acetates. Both react highly regioselectively with lithium cyanocuprates, or enolates. We have recently reported the mUlticoupl
1-Aryl-3-halo-1,3-dienes were prepared from the sequential addition-elimination reaction of 1-aryl-2,3-allenols with LiX (X=Br, Cl) in HOAc in moderate to good yields. Here the aromatic substituent is crucial to this interesting transformation since no reaction was observed with 1-alkyl or perfluoro