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Elimination kinetics of cefotaxime in patients with renal insufficiency requiring dialysis

✍ Scribed by Glockner, W. M.; Hoffler, U.; Kindler, J.; Peters, G.; Sieberth, H. G.


Book ID
124072311
Publisher
Oxford University Press
Year
1980
Tongue
English
Weight
197 KB
Volume
6
Category
Article
ISSN
0305-7453

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The pharmacokinetics of an intravenous injection of disopyramide was studied in five normal subjects and six patients with varying degrees of renal impairment. The elimination rate constant (p) was related to the endogenous creatinine clearance (Cl,,). However, a decrease in / 3 was not observed un