Estrogen regulated expression of the p21
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Soma Mandal; James R. Davie
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Article
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2010
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John Wiley and Sons
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English
β 183 KB
## Abstract The cyclinβdependent kinase inhibitor protein p21^Waf1/Cip1^ is a potent tumor suppressor. Here, we demonstrate that estradiol regulates the p21^Waf1/Cip1^ gene. Estradiol induces p21^Waf1/Cip1^ mRNA expression within 30β60βmin independent of new protein synthesis in the estrogen recept