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Eliciting broadly neutralizing antibodies against HIV-1 that target gp41 MPER

✍ Scribed by D Han, H Habte, Y Qin, K Takamoto, C LaBranche, D Montefiori, MW Cho

Book ID
120691441
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
75 KB
Volume
9
Category
Article
ISSN
1742-4690

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## Abstract During viral entry, the fusogenic state of human immunodeficiency virus Type 1 (HIV‐1) envelope protein gp41 is a quaternary structure consisting of three gp41 glycoproteins, each with two conserved helical domains (N‐HR and C‐HR). Thus far, the examination of monomeric gp41 peptides as