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Elicitation of specific, Th1-biased immune response precludes skeletal muscle damage in cruzipain-vaccinated mice

✍ Scribed by F.M. Frank; S.I. Cazorla; M.J. Sartori; R.S. Corral

Book ID: 113956555
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 975 KB
Volume: 84
Category: Article
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2007.10.004

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## Abstract ## Background CGβ is expressed not only in placenta, but also in a wide range of tumors. To study DNA vaccine based on xenogeneic CGβ for cancer immuno‐therapy, we investigated whether rhesus monkey CGβ (rmCGβ) DNA vaccine could induce protective T‐cell responses and humoral responses