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Elevation of soluble HLA class I antigens in sera of patients with acute and chronic hepatitis

โœ Scribed by Sakaguchi, Kohsaku ;Koide, Norio ;Tsuji, Takao


Publisher
Springer-Verlag
Year
1991
Tongue
English
Weight
63 KB
Volume
26
Category
Article
ISSN
0435-1339

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Patients infected with HIV-1 who are heterozygous at HLA class I loci present greater variety of antigenic peptides to CD8+ cytotoxic T lymphocytes, slowing progression to AIDS. A similar broad immune response in chronic hepatitis C (CHC) infection could result in greater hepatic injury. Although sp