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Elevation of glucose 6-phosphate dehydrogenase activity increases xylitol production in recombinant Saccharomyces cerevisiae

✍ Scribed by Do-Hyun Kwon; Myoung-Dong Kim; Tae-Hee Lee; Yong-Joo Oh; Yeon-Woo Ryu; Jin-Ho Seo


Book ID
113804096
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
145 KB
Volume
43
Category
Article
ISSN
1381-1177

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To enhance metabolite transfer in the two initial sequential steps of xylose metabolism in yeast, two structural genes of Pichia stipitis, XYL } and XYL " encoding xylose reductase (XR) and xylitol dehydrogenase (XDH), respectively, were fused in frame. Four chimeric genes were constructed, encoding