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Elevation of collagen type I in fibroblast–keratinocyte cocultures emphasizes the decisive role of fibroblasts in the manifestation of the phenotype of cyclosporin A-induced gingival overgrowth

✍ Scribed by B. Dannewitz; P. Tomakidi; Y. Syagailo; A. Kohl; H. J. Staehle; P. Eickholz; G. Komposch; T. Steinberg

Book ID
110107475
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
462 KB
Volume
44
Category
Article
ISSN
0022-3484

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Cyclosporin A decreases the degradation
Cyclosporin A decreases the degradation of type I collagen in rat gingival overgrowth
✍ Masatoshi Kataoka; Yasuki Shimizu; Kenji Kunikiyo; Yoji Asahara; Kikuji Yamashit 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 542 KB

Cyclosporin A (CsA) is used as an immunosuppressive agent and its prominent side effect is the induction of fibrous gingival overgrowth. The purpose of this study was to investigate the effect of CsA on the type I collagen metabolism in the gingiva of rats fed a powdered diet either containing or la