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Elevated pyruvate kinase activity in patients with hemolytic anemia due to red cell pyruvate kinase “deficiency”

✍ Scribed by Ernest Beutler; Linda Forman; Ernesto Rios-Larrain


Book ID
115681795
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
582 KB
Volume
83
Category
Article
ISSN
1555-7162

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## Communicated by Mark Paalman Pyruvate kinase (PK) deficiency (PKD) is an autosomal recessive disorder with the typical manifestation of nonspherocytic hemolytic anemia. We analyzed the mutant enzymes of 10 unrelated patients with PKD, whose symptoms ranged from a mild, chronic hemolytic anemia t