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Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-alpha and TNF-alpha in systemic lupus erythematosus

โœ Scribed by Chun-yan Ma; Yu-lian Jiao; Jie Zhang; Qing-rui Yang; Zhi-fen Zhang; Ya-juan Shen; Zi-jiang Chen; Yue-ran Zhao


Publisher
Springer
Year
2010
Tongue
English
Weight
610 KB
Volume
32
Category
Article
ISSN
0172-8172

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Objective. To assess nucleosome plasma levels in patients with systemic lupus erythematosus (SLE) and to study the correlations with serum antinucleosome, anti-double-stranded DNA (anti-dsDNA), and antihistone antibody activities, as well as with disease activity (by the SLE Disease Activity Index [