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Elevated neutral protease activity in myelin from brains of patients with multiple sclerosis

✍ Scribed by Shuzo Sato; Richard H. Quarles; Roscoe O. Brady; Wallace W. Tourtellotte

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
615 KB
Volume
15
Category
Article
ISSN
0364-5134

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## Abstract Oxidative stress has been implicated in the pathophysiology of multiple sclerosis (MS). Increased levels of reactive oxygen species (ROS) derived from infiltrating macrophages and microglial cells have been shown to reduce the levels of endogenous antioxidants and to cause the oxidation