Chronic myeloid leukemia (CML) patients with persistent or relapsed disease following bone-marrow transplantation (BMT) usually show both clonal and non-clonal cytogenetic changes in addition to the Philadelphia (Ph) translocation. These changes are presumably due to conditioning prior to transplant
Elevated levels of soluble ICAM-1 in serum of patients with acute myeloid leukemia undergoing bone marrow transplantation
β Scribed by Maeda, Yasuhiro; Chihara, Junichi; Horiuchi, Fusanari; Miyatake, Jun-ichi; Tatsumi, Yoichi; Urase, Fumiaki; Irimajiri, Kiyohiro; Nakajima, Shigenori; Horiuchi, Atsushi
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 177 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0361-8609
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β¦ Synopsis
Serum soluble ICAM-1 concentrations were measured in 10 patients with or without chronic graft-vs.-host disease (GVHD) after allogeneic bone marrow transplantation. The serum soluble ICAM-1 levels in the patients with chronic GVHD were significantly higher than that in the patients without chronic GVHD. The data indicated that serum soluble ICAM-1 is a useful parameter for predicting chronic GVHD.
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