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Elevated Level of 8-Hydroxydeoxyguanosine in DNA of Liver, Kidneys, and Brain of Long-Evans Cinnamon Rats

✍ Scribed by Yamamoto, Fuyumi ;Kasai, Hiroshi ;Togashi, Yuji ;Takeichi, Noritoshi ;Hori, Tomokatsu ;Nishimura, Susumu


Book ID
108579634
Publisher
Wiley (Blackwell Publishing)
Year
1993
Tongue
English
Weight
261 KB
Volume
84
Category
Article
ISSN
0910-5050

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Decreased expression of liver glutathion
✍ Hiroshi Suemizu; Shinichi Yoshimura; Noritoshi Takeichi; Tetsuya Moriuchi πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 731 KB

The Long-Evans Cinnamon rat is a mutant strain that contracts hereditary hepatitis and, eventually, spontaneous hepatoma. Recently, abnormal copper accumulations in Long-Evans Cinnamon rat livers were shown to be genetically linked to the development of hepatitis. Because reduced glutathione and glu