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Elevated Intracellular Calcium Blocks Programmed Neuronal Death

โœ Scribed by JAMES L. FRANKLIN; EUGENE M. JOHNSON Jr.


Book ID
119871073
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
703 KB
Volume
747
Category
Article
ISSN
0890-6564

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Neuronal injury is intricately linked to the activation of three distinct neuronal endonucleases. Since these endonucleases are exquisitely pH dependent, we investigated in primary rat hippocampal neurons the role of intracellular pH (pH i ) regulation during nitric oxide (NO)-induced toxicity. Neur