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Elevated Interleukin-21 Correlated to Th17 and Th1 Cells in Patients with Immune Thrombocytopenia

✍ Scribed by Xiaojuan Zhu; Daoxin Ma; Jingbo Zhang; Jun Peng; Xun Qu; Chunyan Ji; Ming Hou


Publisher
Springer
Year
2009
Tongue
English
Weight
235 KB
Volume
30
Category
Article
ISSN
0271-9142

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Background: Tumor necrosis factor (TNF)-like protein 1A (TL1A) is a member of the TNF superfamily and contributes to the pathogenesis of Crohn's disease (CD) by stimulating T-helper (Th) 1 cells. In addition to Th1, recent studies have focused on the role of Th17 cells in the pathogenesis of CD. Her